Home Portfolio Services Contact

My Recent Work

Neycher •

Vaginal Dryness: Causes, Symptoms & Why It Matters | Neycher

Vaginal dryness is a common condition that affects many women at different life stages. This article explores the causes and symptoms of vaginal dryness, while our companion article on treating and preventing vaginal dryness provides solutions for finding relief.Have you ever wondered how your body naturally maintains vaginal moisture? Understanding this delicate system helps explain why disruptions can occur and how to address them effectively.Your vagina is lined with specialized epithelial ce...
Neycher •

Condoms and BV: Understanding the Connection & Prevention Tips | Neycher

Ever found yourself wondering if your trusty condoms might be playing a part in those not-so-fun bouts of bacterial vaginosis (BV)? If you're nodding along, you're definitely not alone. It's a common question, and it makes total sense to want to understand what's happening with your body. So, let's dive into what BV is, how condoms fit into the picture, and what you can do to keep your vaginal health in a happy place.‍Simply put, bacterial vaginosis (BV) is a common vaginal condition that happen...
ACS Publications •

Oxygenation by Intravascular Photosynthesis Reduces Kidney Damage During ex Vivo Preservation

Several clinical issues are associated with reduced oxygen delivery to tissues due to impaired vascular perfusion; moreover, organs procured for transplantation are subjected to severe hypoxia during preservation. Consequently, alternative tissue oxygenation is an active field in biomedical research where several innovative approaches have been recently proposed. Among these, intravascular photosynthesis represents a promising approach as it relies on the intrinsic capacity of certain microorgan...
Advanced Therapeutics •

Development of a Hibernation‐Inspired Preservation Strategy to Enhance the Clinical Translation of Photosynthetic Biomaterials

Photosynthetic biomaterials have emerged as a promising approach for delivering oxygen and other bioactive molecules in several biomedical applications. This technology is based on the use of standard biomaterials loaded with photosynthetic cells for the controlled release of oxygen at the target site. However, as well as for other cell-based approaches, a main drawback for their clinical translation is the low shelf-life of living materials. Here, the potential of inducing a dormant hibernation...
MDPI •

Comprehensive Characterization of Tissues Derived from Animals at Different Regenerative Stages: A Comparative Analysis between Fetal and Adult Mouse Skin

All articles published by MDPI are made immediately available worldwide under an open access license. No special
permission is required to reuse all or part of the article published by MDPI, including figures and tables. For
articles published under an open access Creative Common CC BY license, any part of the article may be reused without
permission provided that the original article is clearly cited. For more information, please refer to
https://www.mdpi.com/...
Molecular Therapy •

Enforced dimerization between XBP1s and ATF6f enhances the protective effects of the UPR in models of neurodegeneration

The content on this site is intended for healthcare professionals and researchers across all fields of science.We use cookies to help provide and enhance our service and tailor content. To update your cookie settings, please visit the
Cookie settings for this site.

All content on this site: Copyright © 2025 Elsevier Inc., its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content,...
Front. Physiol •

Frontiers | The Reparative Abilities of Menstrual Stem Cells Modulate the Wound Matrix Signals and Improve Cutaneous Regeneration

Considerable advances have been made toward understanding the cellular and molecular mechanism of wound healing, however, treatments for chronic wounds remain elusive. Emerging concepts utilizing mesenchymal stem cells (MSCs) from umbilical cord, adipose tissue and bone marrow have shown therapeutical advantages for wound healing. Based on this positive outcome, efforts to determine the optimal sources for MSCs are required in order to improve their migratory, angiogenic, immunomodulatory, and r...
Neurobiology of Disease •

Targeting PERK signaling with the small molecule GSK2606414 prevents neurodegeneration in a model of Parkinson's disease

These cells were the focus of our study. The pathogenic role of dysregulated PERK-eIF2α-P signaling in neurons has been well characterized across the spectrum of neurodegenerative disorders (Grande et al., 2018; Halliday et al., 2015, 2017; Hoozemans et al., 2005, 2007; Kim et al., 2014; Mercado et al., 2018; Moreno et al., 2012, 2013; Radford et al., 2015; Stutzbach et al., 2013). PERK-P has been detected in astrocytes from human tauopathy diseases (Nijholt et al., 2012), but the pathogenic eff...
Brain Research •

ER stress and Parkinson's disease: Pathological inputs that converge into the secretory pathway

Cookies are used by this site. Cookie SettingsAll content on this site: Copyright © 2025 Elsevier B.V., its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.

Cookies are used by this site. Cookie Settings

All content on this site: Copyright © 2025 Elsevier B.V., its licensors, and contributors. All rights are reserved, including those for text...
PLOS One •

Functional Role of the Disulfide Isomerase ERp57 in Axonal Regeneration

Citation: Castillo V, Oñate M, Woehlbier U, Rozas P, Andreu C, Medinas D, et al. (2015) Functional Role of the Disulfide Isomerase ERp57 in Axonal Regeneration. PLoS ONE 10(9):
e0136620.

https://doi.org/10.1371/journal.pone.0136620Editor: Thomas H. Gillingwater, University of Edinburgh, UNITED KINGDOMReceived: March 9, 2015; Accepted: August 3, 2015; Published: September 11, 2015Copyright: © 2015 Castillo et al. This is an open access article distributed under the...
Neural Regeneration Research •

Gene therapy in Parkinson's disease: targeting the... : Neural Regeneration Research

Parkinson's disease (PD) is the second most common neurodegenerative disease affecting 1% of the population over 60 years of age. The progressive degeneration of dopaminergic neurons at the substantia nigra pars compacta (SNpc) results in a severe and gradual depletion of dopamine content in the striatum, a phenomena that is responsible for the characteristic motor symptoms of this disease. There is no cure for PD and available treatments only aim to restore dopamine deficits. Administration of...
Frontiers •

Frontiers | ER proteostasis disturbances in Parkinson's disease: novel insights

Parkinson's disease (PD) is characterized by the selective loss of dopaminergic neurons of the substantia nigra pars compacta (SNpc). Proteostasis impairment at the level of the endoplasmic reticulum (ER) is emerging as a driving factor of dopaminergic neuron loss in PD. ER stress engages the activation of an adaptive reaction known as the unfolded protein response (UPR) to recover proteostasis or trigger apoptosis of damaged cells. The therapeutic potential of the UPR as a target has been recen...